Why Make This Recipe
Mac and Cheese Meatloaf Casserole is a fun and comforting dish that combines two classic favorites: meatloaf and macaroni and cheese. It’s perfect for busy weeknights or family gatherings. The recipe is simple to follow, and it delivers rich flavors that everyone will love. Plus, you can easily customize it to suit your taste!
How to Make Mac and Cheese Meatloaf Casserole
Ingredients:
- 1 lb ground beef
- 1 cup macaroni pasta
- 2 cups shredded cheddar cheese
- 1 cup milk
- 1 onion, chopped
- 1 egg
- 1 cup breadcrumbs
- 1 tablespoon Worcestershire sauce
- Salt and pepper to taste
- Optional: additional spices (like garlic powder, paprika)
Directions:
- Preheat the oven to 350°F (175°C).
- Cook macaroni according to package instructions; drain and set aside.
- In a large mixing bowl, combine ground beef, onion, egg, breadcrumbs, Worcestershire sauce, salt, and pepper. Mix until well combined.
- In a separate bowl, mix cooked macaroni with cheese and milk.
- Layer half of the meat mixture in a greased casserole dish, followed by the macaroni and cheese mixture, and then the remaining meat mixture on top.
- Bake for 1 hour or until the meat is cooked through and the top is browned.
- Let it cool for a few minutes before serving.

How to Serve Mac and Cheese Meatloaf Casserole
Serve the Mac and Cheese Meatloaf Casserole hot from the oven. You can add a side salad or some steamed vegetables to make it a complete meal. Leftovers can be stored for easy lunches or dinners throughout the week.
How to Store Mac and Cheese Meatloaf Casserole
If you have leftovers, store them in an airtight container in the refrigerator. It will stay fresh for about 3 to 4 days. You can also freeze the casserole for longer storage, up to 3 months. Just make sure to cover it well to prevent freezer burn.
Tips to Make Mac and Cheese Meatloaf Casserole
- Use a mix of cheeses for added flavor or to use up what you have on hand.
- If you want a bit more spice, consider adding chili powder or hot sauce to the meat mixture.
- For more vegetables, you can include chopped bell peppers or spinach in the meat mixture.
Variation
You can substitute ground turkey or chicken for the beef if you prefer a lighter option. Additionally, you can use gluten-free pasta to make this dish suitable for those with gluten sensitivities.
FAQs
Can I make this casserole ahead of time?
Yes! You can prepare the casserole in advance and store it in the refrigerator. Just bake it when you’re ready to eat.
What else can I add to the casserole?
Feel free to add any veggies you like, or try different types of cheese for a unique flavor.
Can I reheat leftovers in the microwave?
Yes, you can reheat leftovers in the microwave. Just make sure to cover it to keep moisture in and heat it in short intervals, stirring occasionally.

Mac and Cheese Meatloaf Casserole
- Total Time: 75 minutes
- Yield: 6 servings
- Diet: None
Description
A fun and comforting dish that combines meatloaf and macaroni and cheese, perfect for busy weeknights or family gatherings.
Ingredients
- 1 lb ground beef
- 1 cup macaroni pasta
- 2 cups shredded cheddar cheese
- 1 cup milk
- 1 onion, chopped
- 1 egg
- 1 cup breadcrumbs
- 1 tablespoon Worcestershire sauce
- Salt and pepper to taste
- Optional: additional spices (like garlic powder, paprika)
Instructions
- Preheat the oven to 350°F (175°C).
- Cook macaroni according to package instructions; drain and set aside.
- In a large mixing bowl, combine ground beef, onion, egg, breadcrumbs, Worcestershire sauce, salt, and pepper. Mix until well combined.
- In a separate bowl, mix cooked macaroni with cheese and milk.
- Layer half of the meat mixture in a greased casserole dish, followed by the macaroni and cheese mixture, and then the remaining meat mixture on top.
- Bake for 1 hour or until the meat is cooked through and the top is browned.
- Let it cool for a few minutes before serving.
Notes
Leftovers can be stored for 3-4 days in the refrigerator or frozen for up to 3 months.
- Prep Time: 15 minutes
- Cook Time: 60 minutes
- Category: Main Course
- Method: Baking
- Cuisine: American



